Bilateral elevation of TNFa and IL-6 mRNAs in dorsal root ganglia alongside neuroaxis following unilateral nerve injury
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Rok publikování | 2011 |
Druh | Konferenční abstrakty |
Fakulta / Pracoviště MU | |
Citace | |
Popis | Cytokines are injury-induced inflammatory mediators that contribute to both induction and maintenance of neuropathic pain. We used in situ hybridization and quanitative RT-PCR to provide evidence that unilateral chronic constriction injury (CCI) of the sciatic nerve induces synthesis of TNFa and IL-6 in DRG of different spinal cord segments alongside neuroaxis. |
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