Nukleotidové polymorfismy u blízce příbuzných treponem a jejich detekce
Autoři | |
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Rok publikování | 2004 |
Druh | Článek ve sborníku |
Konference | Sborník abstraktů XIII. konference mladých mikrobiologů Tomáškovy dny 2004 |
Fakulta / Pracoviště MU | |
Citace | |
Obor | Genetika a molekulární biologie |
Klíčová slova | T. pallidum; DNA microarray technology |
Popis | When comparing genomes of T. pallidum subspecies, no extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts). Anotace anglicky: No extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts). |
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