Nukleotidové polymorfismy u blízce příbuzných treponem a jejich detekce
| Title in English | Nucleotide polytmorphisms in genomes of closely related treponemes and their detection |
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| Authors | |
| Year of publication | 2004 |
| Type | Article in Proceedings |
| Conference | Sborník abstraktů XIII. konference mladých mikrobiologů Tomáškovy dny 2004 |
| MU Faculty or unit | |
| Citation | |
| Field | Genetics and molecular biology |
| Keywords | T. pallidum; DNA microarray technology |
| Description | When comparing genomes of T. pallidum subspecies, no extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts). Anotace anglicky: No extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts). |
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