Monofunctionalized Fluorinated Bambusurils and Their Conjugates for Anion Transport and Extraction

• Autoři: DE SIMONE Nicola Alessandro; CHVOJKA Matúš; LAPEŠOVÁ Jana; MARTÍNEZ-CRESPO Luis; SLÁVIK Petr; SOKOLOV Jan; BUTLER Stephen J.; VALKENIER Hennie; ŠINDELÁŘ Vladimír
• Rok publikování: 2022
• Druh: Článek v odborném periodiku
• Časopis / Zdroj: Journal of Organic Chemistry
• Fakulta / Pracoviště MU: Přírodovědecká fakulta
• www: https://doi.org/10.1021/acs.joc.2c00870
• Doi: http://dx.doi.org/10.1021/acs.joc.2c00870
• Klíčová slova: Anions; Assays; Extraction; Macrocycles; Reaction products
• Popis: Bambusurils are macrocyclic molecules that are known for their high binding affinity and selectivity toward anions. Here, we present the preparation of two bambusurils bearing fluorinated substituents and one carboxylic function. These monofunctionalized bambusurils were conjugated with crown ether and cholesterol units. The resulting conjugates were successfully tested in liquid–liquid extraction of inorganic salts and chloride/bicarbonate transport across lipid bilayers.

Související projekty

• CETOCOEN Excellence
• CETOCOEN Excellence
• Czech Infrastructure for Integrative Structural Biology
• Monofunkcializované bambusurily a jejich supramolekulární vlastnosti
• RECETOX RI