Human native endocarditis caused by Streptococcus canis-a case report

Varování

Publikace nespadá pod Ekonomicko-správní fakultu, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.

Autoři	MALIŠOVÁ Barbora ŠANTAVÝ Petr LOVEČKOVÁ Yvona HLADKÝ Bořivoj KOTÁSKOVÁ Iva POL Jiří LONSKÝ Vladimír NĚMEC Petr FREIBERGER Tomáš
Rok publikování	2019
Druh	Článek v odborném periodiku
Časopis / Zdroj	Journal of Pathology, Microbiology and Immunology, APMIS
Fakulta / Pracoviště MU	Lékařská fakulta
Citace
www	http://dx.doi.org/10.1111/apm.12905
Doi	http://dx.doi.org/10.1111/apm.12905
Klíčová slova	Streptococcus canis; infective endocarditis; PCR; sequencing
Popis	We report a very rare case of Streptococcus canis native infective endocarditis in a 73-year-old woman living in close con- tact with her dog. Her echocardiography showed large calcifications in the mitral annulus, massive regurgitation below the posterior leaflet, and adjacent vegetation. Blood culture was positive for Streptococcus Lancefield group G. A coronary artery bypass and mitral valve replacement had to be done. Streptococcus canis was detected in a heart valve using a broad range PCR followed by 16S rRNA and confirmed by tuf gene sequencing, while tissue culture remained negative. The patient was not bitten by her dog nor did she have comorbidities or skin ulcers. She fully recovered.
Související projekty:	Poruchy tvorby protilátek a komplementového systému Vrozené a získané deficience imunitního systému