Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
-
Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
-
Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 239
2018
-
Bambusurils Bearing Nitro Groups and Their Further Modifications
European Journal of Organic Chemistry, rok: 2018, ročník: Neuveden, vydání: 1, DOI
-
Bio-Inspired Hydro-Pressure Consolidation of Silica
Advanced Functional Materials, rok: 2018, ročník: 28, vydání: 48, DOI
-
BioSAXS practical course
Rok: 2018, druh: Uspořádání workshopu
-
BUT students from Faculty of chemistry
Rok: 2018, druh: Popularizační texty
-
Comparative investigation of toxicity and bioaccumulation of Cd-based quantum dots and Cd salt in freshwater plant Lemna minor L.
Ecotoxicology and Environmental Safety, rok: 2018, ročník: 147, vydání: JAN 2018, DOI
-
Complete genome sequences of two strains of Treponema pallidum subsp pertenue from Indonesia: Modular structure of several treponemal genes
PLoS neglected tropical diseases, rok: 2018, ročník: 12, vydání: 10, DOI
-
Controlled synthesis and characterization of metal alloy nanoparticles and their size-dependent phase diagrams
Rok: 2018, druh: Konferenční abstrakty
-
Cryopreserved Cells Regeneration Monitored by Atomic Force Microscopy and Correlated With State of Cytoskeleton and Nuclear Membrane
IEEE TRANSACTIONS ON NANOBIOSCIENCE, rok: 2018, ročník: 17, vydání: 4, DOI
-
Cyclopropylamine plasma polymer surfaces for label-free SPR and QCM immunosensing of Salmonella
Sensors and Actuators B: Chemical, rok: 2018, ročník: 276, vydání: DEC, DOI
-
Description and comparative genomics of Macrococcus caseolyticus subsp. hominis subsp. nov., Macrococcus goetzii sp. nov., Macrococcus epidermidis sp. nov., and Macrococcus bohemicus sp. nov., novel macrococci from human clinical material with virulence potential and suspected uptake of foreign DNA by natural transformation
Frontiers in Microbiology, rok: 2018, ročník: 9, vydání: 1178, DOI