Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
-
Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
-
Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 252
2023
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Aerosol-assisted sol–gel synthesis of mesoporous Ag–Ta–SiO2 catalysts for the direct upgrading of ethanol to butadiene
RSC Sustainability, rok: 2023, ročník: 1, vydání: 3, DOI
2022
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Airborne Preparation of Small Gold Nanoparticles Dispersed on Mesoporous Silica for the Catalytic Oxidation of Glycerol to Dihydroxyacetone
ACS Applied Nano Materials, rok: 2022, ročník: 5, vydání: 12, DOI
2021
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Acetylace 7-hydroxy skupiny dibenzocyklooktadienových lignanů zvyšuje inhibici P-glykoproteinu
Rok: 2021, druh: Konferenční abstrakty
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In-Cell NMR Spectroscopy of Functional Riboswitch Aptamers in Eukaryotic Cells
Angewandte Chemie International Edition, rok: 2021, ročník: 60, vydání: 2, DOI
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One-pot synthesis of 1-aryl-2-amino alcohols from the corresponding amides or nitriles
Rok: 2021, druh: Další prezentace na konferencích
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Unexpected formation of 1-aryl-2-aminoalcohols during reductions of the corresponding amides and nitriles
Rok: 2021, druh: Další prezentace na konferencích
2020
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Conformational flexibility in amidophosphoesters: a CSD analysis completed with two new crystal structures of (C6H5O)2P(O)X [X = NHC7H13 and N(CH2C6H5)2]
Acta Crystallographica Section C: Structural Chemistry, rok: 2020, ročník: 76, vydání: 1, DOI
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Demonstration of electron diffraction from membrane protein crystals grown in a lipidic mesophase after lamella preparation by focused ion beam milling at cryogenic temperatures
Journal of Applied Crystallography, rok: 2020, ročník: 53, vydání: DEC, DOI
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Heterometallic 3d-4f {Co2Gd4} phosphonates: new members of the potential magnetic cooler family
New Journal of Chemistry, rok: 2020, ročník: 44, vydání: 2, DOI
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Mildly acidic aluminosilicate catalysts for stable performance in ethanol dehydration
Applied Catalysis B: Environmental, rok: 2020, ročník: 271, vydání: August 2020, DOI