Informace o projektu
Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Kód projektu
- LM2015043
- Období řešení
- 1/2016 - 12/2019
- Investor / Programový rámec / typ projektu
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Ministerstvo školství, mládeže a tělovýchovy ČR
- Velké infrastruktury pro výzkum, vývoj a inovace
- Fakulta / Pracoviště MU
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Středoevropský technologický institut
- prof. RNDr. Vladimír Sklenář, DrSc.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed infrastructure of the core facilities and central laboratories of CEITEC (Central European Institute of Technology, Brno) and BIOCEV (Biotechnology and Biomedicine Centre, Vestec, Prague-West) providing expertise and access to technologies used for integrative approaches to structural analysis of biologically important cellular components and macromolecules - proteins, nucleic acids, and their complexes. CIISB, equipped with the cutting-edge technologies (total investments will exceed 750 mil. CZK by the end of 2015), will offer access to the equipment and expertise in the following fields: high-field NMR spectroscopy; high throughput crystallization of biological macromolecules; X-ray diffraction techniques; Bio-SAXS measurements; AFM imaging; characterization of proteins, nucleic acids and complexes by biophysical methods including microcalorimetry, dynamic light scattering, and surface plasmon resonance; high-end cryo-electron microscopy and tomography allowing studies of cellular structures, organelles, and biomacromolecular complexes by 3D imaging; protein expression in eukaryotic cells; high-end mass spectrometry characterization of biomacromolecules; determination of protein post-translational modifications; MS-based peptide mapping/sequencing; high throughput sequencing and proteomic services. CIISB infrastructure aims to provide a high quality open access services in provision of methods and techniques on a level of national and trans-national importance. CIISB as National Affiliated Center is a part of the ESFRI projects INSTRUCT.
Publikace
Počet publikací: 251
2017
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MU students from Faculty of Science
Rok: 2017, druh: Popularizační texty
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Návštěva středoškolských studentů v CF CEITEC MU
Rok: 2017, druh: Popularizační texty
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New Adamantane-like Silicophosphate Cage and Its Reactivity toward Tris(pentafluorophenyl)borane
Inorganic Chemistry, rok: 2017, ročník: 56, vydání: 17, DOI
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Newly identified bangle lectin from Photorhabdus asymbiotica and its role in pathogenesis
Rok: 2017, druh: Další prezentace na konferencích
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Non-hydrolytic synthesis of porous aluminosilicates and –phosphates
Rok: 2017, druh: Konferenční abstrakty
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Novel bangle lectin from Photorhabdus asymbiotica: sugar-binding specificity, structure and interaction with host immune system
Rok: 2017, druh: Konferenční abstrakty
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Open day
Rok: 2017, druh: Popularizační texty
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P-glycoprotein inhibition by dibenzocyclooctadiene lignans from Schisandra chinensis
Rok: 2017, druh: Konferenční abstrakty
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Phase Equilibria in the System CuO-NiO-P4O10 and Synthesis, Crystal Structure, and Characterization of the New Copper Nickel Oxide Phosphate Cu3NiO(PO4)(2)
Zeitschrift für anorganische und allgemeine Chemie, rok: 2017, ročník: 643, vydání: 4, DOI
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Phosphorylation of the regulatory domain of human tyrosine hydroxylase 1 monitored using non-uniformly sampled NMR
Biophysical Chemistry, rok: 2017, ročník: 223, vydání: April, DOI