Informace o projektu
Laboratoř struktury a dynamiky biomolekul
- Kód projektu
- VS96095
- Období řešení
- 7/1996 - 12/2000
- Investor / Programový rámec / typ projektu
-
Ministerstvo školství, mládeže a tělovýchovy ČR
- Posílení výzkumu na vysokých školách
- Fakulta / Pracoviště MU
-
Přírodovědecká fakulta
- prof. RNDr. Jaroslav Koča, DrSc.
The subject of the proposal is to create Laboratory of Biomolecular Structure and Dynamics. An efficient scientific program is proposed, which will ensure that two recent large investment activities (the supercomputer project and the NMR instrument) will efficiently be used. The project is a combination of NMR spectroscopy, X-ray crystallography and computer modeling. The scientific goals include both methodoly development and its applications on biologically interesting molecules. The systems studied will include oligonucleotides, peptides, carbohydrates, nucleotide-sugars, and proteins. The strategical direction for high technology will be biodegradation in the environment.
Publikace
Počet publikací: 27
1999
-
15N NMR study of isoquinoline alkaloids
Magnetic Resonance in Chemistry, rok: 1999, ročník: 37, vydání: 3
-
1H and 13C NMR Study of Quaternary Benzo[c]phenanthridine Alkaloids
Magnetic Resonance in Chemistry, rok: 1999, ročník: 37, vydání: 11
-
Comparison of conformational behavior of the short alanine peptides and their boron analogues
Journal of Molecular Structure (Theochem), rok: 1999, ročník: 489, vydání: 2--3
-
Differences in Conformational Behavior of ATA and TAT Sequences in Single Strand DNA Trimer
Journal of Biomolecular Structure and Dynamics, rok: 1999, ročník: 16, vydání: 5
-
Differentiation Between Isomeric Phenylglycidyl Ether Adducts of 2´-Deoxyguanosine and 2´-Deoxyguanosine-5´-monophosphate Using Liquid Chromatography/Electrospray Tandem Mass Spectrometry
Journal of Mass Spectrometry, rok: 1999, ročník: 34, vydání: 8
-
Pyridoxine as a Substrate for Screening Synthetic Potential of Glycosidases
Collection of Czechoslovak Chemical Communications, rok: 1999, ročník: 64, vydání: 8
-
Regioselective preparation of N7- and N9-alkyl derivatives of N6-[(Dimethylamino)methylene]adenine bearing active methylene group and their further derivatization leading to alpha-branched acyclic nucleotide analogues
European Journal of Organic Chemistry, rok: 1999, ročník: 1999, vydání: 10
1998
-
Sanguinarine Pseudobase: Re-examination of NMR Assignments Using Gradient-Enhanced Spectroscopy
Magnetic Resonance in Chemistry, rok: 1998, ročník: 36, vydání: 11
-
Structural Studies of Chelirubine and Chelilutine Free Bases
Collection of Czechoslovak Chemical Communications, rok: 1998, ročník: 63, vydání: 7
-
Structure and Transformations of the Alkaloid Sanguilutine
Phytochemistry, rok: 1998, ročník: 47, vydání: 5