Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 97
2024
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Transmembrane glycoprotein GPNMB is a candidate predictive biomarker and potentially a therapeutic target in metastatic renal cell carcinoma
Year: 2024, type: Conference abstract
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Unsymmetric Chiral Ligands for Large Metallo-Macrocycles: Selectivity of Orientational Self-Sorting
Angewandte Chemie International Edition, year: 2024, volume: 63, edition: 36, DOI
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Upconversion Nanoparticle-Based Dot-Blot Immunoassay for Quantitative Biomarker Detection
Analytical Chemistry, year: 2024, volume: 96, edition: 25, DOI
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YAP Signaling Regulates the Cellular Uptake and Therapeutic Effect of Nanoparticles
Advanced Science, year: 2024, volume: 11, edition: 2, DOI
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Zero-field splitting in tetracoordinate Co(II) complexes containing heterocyclic aromatic ligands
Journal of Molecular Structure, year: 2024, volume: 1295, edition: Jan, DOI
2023
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36th Central European NMR Meeting, NMR Valtice 2023
Year: 2023, type: Conference
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3rd CEITEC Symposium on Recent Advances in Cryo-EM
Year: 2023, type: Conference
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A comparative assessment of a piezoelectric biosensor based on a new antifouling nanolayer and cultivation methods: Enhancing S. aureus detection in fresh dairy products
Current Research in Biotechnology, year: 2023, volume: 6, edition: November, DOI
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Advanced Microscopic and Biosensing Approaches for Monitoring Bacteriophage-Mediated Lysis of Bacteria
Year: 2023, type: Conference abstract
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ARBRE–Association of Resources for Biophysical Research in Europe
Year: 2023, type: Conference abstract