Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 97
2024
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pH-Dependent oligomerisation of γ-conglutin: A key element to understand its molecular mechanism of action
Food Hydrocolloids, year: 2024, volume: 147, edition: A, DOI
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Pre-existing cell subpopulations in primary prostate cancer tumors display surface fingerprints of docetaxel-resistant cells
CELLULAR ONCOLOGY, year: 2024, DOI
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Preparation of Alzheimer's-disease-relevant Tau protein in HEK293 mammalian cells
Year: 2024, type: Conference abstract
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Proteomic analysis of ascitic extracellular vesicles describes tumour microenvironment and predicts patient survival in ovarian cancer
Journal of Extracellular Vesicles, year: 2024, volume: 13, edition: 3, DOI
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Proteomic Profile of Flaxseed (Linum usitatissimum L.) Products as Influenced by Protein Concentration Method and Cultivar
FOODS, year: 2024, volume: 13, edition: 9, DOI
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Proteomic Profiles of Whole Seeds, Hulls, and Dehulled Seeds of Two Industrial Hemp (Cannabis sativa L.) Cultivars
PLANTS-BASEL, year: 2024, volume: 13, edition: 1, DOI
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Revealing the Effect of Host-Guest Complementarity in Supramolecular Monofunctional Platinum(II) Drugs
Inorganic Chemistry Frontiers, year: 2024, volume: 11, edition: 23, DOI
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Structure and replication of <i>Pseudomonas aeruginosa</i> phage JBD30
EMBO Journal, year: 2024, DOI
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Synthetically-primed adaptation of Pseudomonas putida to a non-native substrate D-xylose
Nature Communications, year: 2024, volume: 15, edition: March 2024, DOI
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The structure of immature tick-borne encephalitis virussupports the collapse model of flavivirus maturation