Project information
CIISB - Czech Infrastructure for Integrative Structural Biology
(CIISB)
- Project Identification
- LM2023042
- Project Period
- 1/2023 - 12/2026
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Large Infrastructures for Research, Development and Innovation
- MU Faculty or unit
- Central European Institute of Technology
- Project Website
- https://www.ciisb.org/
- Cooperating Organization
-
Institute of Biotechnology CAS
- Responsible person Ing. Jan Dohnálek, PhD.
The Czech Infrastructure for Integrative Structural Biology (CIISB) is a distributed national infrastructure, which consists of two nodes, one represented by CEITEC (Central European Institute of Technology, Brno) and second by BIOCEV (Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University, Vestec near Prague). CIISB offers access to 10 core facilities; five of them are part of the Centre of Structural Biology and one of the Mendel Centre of Genomics and Proteomics of Plants of CEITEC Masaryk University and four of the Centre of Molecular Structure of the Institute of Biotechnology AS CR in the BIOCEV Centre.
All CIISB core facilities are in the full operational phase. Projects as OP RDI (Start-up) supported the construction phase, and the built capacities were made available by both CIISB nodes in the form of Open Access to internal and external users. In its construction phase, CIISB (2011-2015) was the Associated National Center of the pan-European research infrastructure INSTRUCT. In 2016, following the completion, putting into operation, and subsequent international evaluation, CIISB became a fully-fledged Instruct-CZ Centre for this distributed infrastructure.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 97
2024
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Hiding in plain sight: Complex interaction patterns between Tau and 14-3-3zeta protein variants
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, year: 2024, volume: 266, edition: Pt 2, DOI
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How does phosphorylation affect interaction between 14-3-3ζ and Tau proteins?
Year: 2024, type: Conference abstract
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Hyaluronic Acid Nanoparticles with Parameters Required for In Vivo Applications: From Synthesis to Parametrization
Biomacromolecules, year: 2024, volume: 25, edition: 8, DOI
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Hyaluronic acid-based hydrogels with tunable mechanics improved structural and contractile properties of cells
Biomaterials Advances, year: 2024, volume: 159, edition: May 2024, DOI
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In-cell NMR suggests that DNA i-motif levels are strongly depleted in living human cells
Nature Communications, year: 2024, volume: 15, edition: 1, DOI
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Insight into antibacterial effect of titanium nanotubular surfaces with focus on Staphylococcus aureus and Pseudomonas aeruginosa
Scientific Reports, year: 2024, volume: 14, edition: 1, DOI
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Lewis Acidic Aluminosilicates: Synthesis, 27Al MQ/MAS NMR, and DFT-Calculated 27Al NMR Parameters
Inorganic Chemistry, year: 2024, volume: 63, edition: 5, DOI
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Long-term zinc treatment alters the mechanical properties and metabolism of prostate cancer cells
Cancer Cell International, year: 2024, volume: 24, edition: 1, DOI
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Multimodal Microscopy Workshop: Probing the Triad of Structure, Mechanics, and Chemistry in Biological Systems 2024
Year: 2024, type: Workshop
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Optimizing ChIRP-MS for Comprehensive Profiling of RNA-Protein Interactions in Arabidopsis thaliana: A Telomerase RNA Case Study
Plants, year: 2024, volume: 13, edition: 6, DOI