Project information
Molecular basis of cell and tissue regulations
- Project Identification
- MSM0021622415
- Project Period
- 1/2005 - 12/2011
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Research Intents
- MU Faculty or unit
- Central European Institute of Technology
- Other MU Faculty/Unit
- Faculty of Medicine
- Keywords
- Cell; genomics; proteomics; biomedicine; gene expression; regulation mechanisms; chromatin structure; structure and interactions of biomolecules
The cell is a system in which each molecule is a component of interaction network. Due to the highly complex interconnection, function of cells and organisms is relatively resistant to failure of individual components of the network. Convergence of thought and methodical approaches which is characteristic for today’s postgenomic era, is a basis for interconnection of research capacities of molecular-biology oriented workgroups of the Masaryk University in the proposed Research Plan (RP). Solving of the RP will proceed in 4 program areas: 1. Regulation mechanisms in animal cells; 2. Functional domains of eukaryotic chromosomes; 3. Genomics and proteomics of regulation circuits in plants; 4. Functional analysis of the genome of clinically and biotechnologically important bacteria. The RP objective is to use approaches of structural biology, functional genomics, proteomics and bioinformatics to elucidate molecular basis of processes which are important from the viewpoint of perspective biomedical and biotechnology applications.
Publications
Total number of publications: 1209
2005
-
Morfologické, imunohistologické a molekulárně patologické nálezy u lymfomu z plášťových buněk
XIX. olomoucké hematologické dny, year: 2005
-
Multiplex PCR for detection of three exfoliative toxin serotype genes in <I>Staphylococcus aureus</I>
Folia Microbiologica, year: 2005, volume: 50, edition: 6
-
Myotonická dystrofie typ 2: vzácné nebo časté onemocnění v České republice?
Česká a slovenská neurologie a neurochirurgie, year: 2005, volume: 68/101, edition: 6
-
Nádorová biologie meduloblastomu: výsledky vyšetření vybraných molekulárně genetických a cytogenetických znaků na Klinice dětské onkologie FN Brno.
15. konference dětských hematologů a onkologů ČR a SR, year: 2005
-
Nádorový supresor p53 zastavuje proliferaci a indukuje diferenciaci monoblastů BM2
Informační listy Genetické společnosti Gregora Mendela, year: 2005
-
Nestin distribution pattern in GM7 glioblastoma cells.
Cellular and Molecular Biology 51, Suppl. - 4th World Congress of Cell and Molecular Biology, year: 2005
-
NMR study of the [VO(O2)2F]2- ion in solution: Synthesis, vibrational spectra and crystal structure of [NH3CH2CH2NH3][VO(O2)2F]
Journal of Fluorine Chemistry, year: 2005, volume: 126, edition: 9-10
-
Nový český stafylokok, <I>Staphylococcus simiae</I>
Zprávy Centra epidemiologie a mikrobiologie, year: 2005, volume: 14, edition: 9
-
Obtaining DNA markers for diversity evaluation in Trifolium pratense cultivars
Book of Abstracts, 6th International Symposium in the Series Recent Advances in Plant Biotechnology, 12.-16.9.2005, year: 2005
-
Occurrence of vancomycin-resistant enterococci in humans and animals in the Czech Republic between 2002 and 2004
Journal of Medical Microbiology, year: 2005, volume: 54, edition: 10