MicroRNA and Glial Tumors: Tiny Relation with Great Potential

Varování

Publikace nespadá pod Ekonomicko-správní fakultu, ale pod Středoevropský technologický institut. Oficiální stránka publikace je na webu muni.cz.

Autoři	ŠÁNA Jiří HAJDÚCH Marian SLABÝ Ondřej
Rok publikování	2012
Druh	Kapitola v knize
Fakulta / Pracoviště MU	Středoevropský technologický institut
Citace
Popis	MicroRNAs (miRNAs) are endogenously expressed small non-coding RNAs that act as post-transcriptional regulators of gene expression. Dysregulation of these molecules has been observed in many types of cancers. Altered expression levels of several miRNAs were identified also in gliomas. It was many times showed that miRNAs are involved in core signaling pathways, which play roles in crucial cellular processes, such as proliferation, apoptosis, cell cycle regulation, invasion, angiogenesis and stem cell behaviour. Therefore, miRNAs have a great potential for oncodiagnostic as well as could be promising therapeutic targets in gliomas.
Související projekty:	CEITEC - středoevropský technologický institut