Estrogenic activity in extracts and exudates of cyanobacteria and green algae.

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Publikace nespadá pod Ekonomicko-správní fakultu, ale pod Přírodovědeckou fakultu. Oficiální stránka publikace je na webu muni.cz.
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SYCHROVÁ Eliška ŠTĚPÁNKOVÁ Tereza NOVÁKOVÁ Kateřina BLÁHA Luděk GIESY J. P. HILSCHEROVÁ Klára

Rok publikování 2012
Druh Článek v odborném periodiku
Časopis / Zdroj Environment International
Fakulta / Pracoviště MU

Přírodovědecká fakulta

Citace
Doi http://dx.doi.org/10.1016/j.envint.2011.10.004
Obor Znečištění a kontrola vody
Klíčová slova Cyanobacteria; Eutrophication; Endocrine disruption; Estrogenicity; Algae; Phytoplankton
Popis Most exudates from cyanobacteria and algae were estrogenic with potencies expressed at 50% of the maximum response under control of the estrogen receptor ranging from 0.2 to 7.2 ng 17 beta-estradiol (E-2) equivalents (EEQ)/L. The greatest estrogenic potency was observed for common species Microcystis aerigunosa. Aqueous extracts of green algae and one species of cyanobacteria (Aphanizomenon gracile) elicited significant estrogenicity with EEQ ranging from 15 to 280 ng 17 beta-estradiol (E-2)/g dry weight. Scenedesmus quadricauda exudates and extracts of Aphanizomenon flos-aquae were antagonistic to the ER when coexposed to E2. The EEQ potency was not correlated with concentrations of cyanotoxins, such as microcystin and cylindrospermopsin, which suggests that the EEQ was comprised of other compounds. The study demonstrates some differences between the estrogenic potency of aqueous extracts prepared from the same species, but of different origin, while the effects of exudates were comparable within species.
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