Vliv iontové síly na protonační rovnováhu 6-benzylaminopurinu
| Autoři | |
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| Rok publikování | 2011 |
| Druh | Článek ve sborníku |
| Konference | XXXI. Moderní Elektrochemické Metody |
| Fakulta / Pracoviště MU | |
| Citace | |
| Obor | Fyzikální chemie a teoretická chemie |
| Klíčová slova | Cytokinins;phytohormones;6–benzylaminopurine;Antitumor activity;Potentiometric titration;Cyclic voltammetry;protonation constants;Reduction potential;Electrode process |
| Popis | Derivatives of adenine, known as cytokinins (CKs), are one of the five major groups of phytohormones, which support cell division, bud formation, branching of stems, and metabolism of plants. One of the most important cytokinins, 6–benzylaminopurine (6–BAP), was studied by two electrochemical methods, potentiometry and voltammetry. Attention was paid to the effect of ionic strength on their behaviour in water–methanol solutions. Potentiometric titrations enabled to determine the protonation constants (pKa) and voltammetric study (linear sweep voltammetry – LSV and elimination voltammetry with linear scan – EVLS) allowed to determine not only their reduction potentials but also deeper evaluation of their reduction processes. Due to potential antitumor activity of derivatives of 6–BAP it is very important to gain further insight into the mechanism of reduction depending on two parameters such as pH and ionic strength, which play a significant role in a living organism. |
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