Bilateral and multiple non-syndromic dentigerous cysts – are they that rare?

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Publikace nespadá pod Ekonomicko-správní fakultu, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.
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SZÁRAZ Dávid DANĚK Zdeněk MACHÁČEK Ctirad BOŘILOVÁ LINHARTOVÁ Petra

Rok publikování 2023
Druh Konferenční abstrakty
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
Popis Background: Dentigerous cysts (DCs) are the most common developmental odontogenic cysts (OCs) and the second most common cysts of the jaws. Bilateral and multiple DCs are usually associated with various syndromes, such as mucopolysaccharidoses or cleidocranial dysplasia; however, they are generally considered to be rare (1.8 – 3 %) in non-syndromic patients. Objectives: Here, we aimed to investigate the incidence of bilateral and multiple DCs in our cohort of patients with OCs. Methods: Patients with suspected OCs examined in 2022 at the University Hospital Brno and meeting all of the following criteria were included in the study: i) well-circumscribed translucency of the cyst associated with an impacted tooth on the OPG, ii) histopathological confirmation of OC. Patients with recurrent cysts were excluded from the study. Findings: In total, 48 patients with newly diagnosed developmental OCs were identified. 7 patients had an odontogenic keratocyst (mean age 37.8 years, 66.6% of men) and 41 patients met the criteria for DCs (mean age 43.9 years, 65.9 % of men); none of the DC patients suffered from a syndrome. Bilateral DCs adjacent to the lower wisdom teeth were presented in 2 patients, another patient had multiple DCs located around upper right wisdom tooth and the lower third molars. Our findings showed that 7.3 % of patients with a DC presented multiple DCs. Conclusion: While multiple DCs are rarer than sporadic single DCs, we suggest avoiding phrases such as “extremely rare” for describing the occurrence of multiple non-syndromic DCs. Compared to some other rare multiple developmental OCs such as the orthokeratinizing odontogenic cyst, multiple non-syndromic DCs are much more common.
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