The Effect of CNQX on Self-Administration: Present in Nicotine, Absent in Methamphetamine Model
Název česky | Vliv CNQX na autoaplikaci: U nikotinového modelu je přítomen, u metamfetaminového chybí |
---|---|
Autoři | |
Rok publikování | 2024 |
Druh | Článek v odborném periodiku |
Časopis / Zdroj | FRONTIERS IN BEHAVIORAL NEUROSCIENCE |
Fakulta / Pracoviště MU | |
Citace | |
www | https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1305412/full |
Doi | http://dx.doi.org/10.3389/fnbeh.2023.1305412 |
Klíčová slova | AMPA/kainate receptor; CNQX; Nicotine; Methamphetamine; Self-administration; Relapse |
Popis | CNQX significantly reduced nicotine intake during the maintenance phase, but no effect was revealed on nicotine seeking after forced abstinence. CNQX did not affect methamphetamine taking or seeking. The effect of reducing nicotine taking but not seeking could be explained by different involvement of glutamatergic receptors in various stages of nicotine dependence. |
Související projekty: |