Chronic venous insufficiency and venous leg ulcers: Aetiology, on the pathophysiology-based treatment

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Publikace nespadá pod Ekonomicko-správní fakultu, ale pod Lékařskou fakultu. Oficiální stránka publikace je na webu muni.cz.
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KRIŽANOVÁ Oľga PENESOVA Adela HOKYNKOVÁ Alica POKORNÁ Andrea SAMADIAN Amir BABULA Petr

Rok publikování 2024
Druh Článek v odborném periodiku
Časopis / Zdroj International Wound Journal
Fakulta / Pracoviště MU

Lékařská fakulta

Citace
www https://onlinelibrary.wiley.com/doi/full/10.1111/iwj.14405
Doi http://dx.doi.org/10.1111/iwj.14405
Klíčová slova chronic venous insufficiency; compression therapy; therapy; venous leg ulcers; wound coverage
Popis The chronic venous disease covers a wide spectrum of venous disorders that are characterized by severely impaired blood return that primarily affects veins in the lower extremities. Morphological and functional abnormalities of the venous system led to chronic venous insufficiency (CVI), and present as leg heaviness/achiness, edema, telangiectasia, and varices. The term 'chronic venous insufficiency' (CVI) refers to a disease of greater severity. Venous dysfunction is associated with venous hypertension and is associated with venous reflux due to poorly functioning or incompetent venous valves, which ultimately reduces venous return, leading to a cascade of morphological, physiological, and histologic abnormalities such as blood pooling, hypoxia, inflammation, swelling, skin changes (lipodermatosclerosis), and in severe cases, venous leg ulcers (VLU). This review summarizes recent knowledge about the aetiology, risk factors, and pathophysiology of VLU and compared the possibilities of their treatment.
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