Cardiovascular Diseases
Autoři | |
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Rok publikování | 2023 |
Druh | Kapitola v knize |
Fakulta / Pracoviště MU | |
Citace | PEŠL, Martin, Jan PŘIBYL, Petr DVOŘÁK, Zdeněk STÁREK, Petr SKLÁDAL, Kristián BRAT a Vladimír ROTREKL. Cardiovascular Diseases. Online. In Malgorzata Lekka, Daniel Navajas, Manfred Radmacher and Alessandro Podestà. Mechanics in Diseased Cells and Tissues, Volume 2 Biomedical Applications. Berlin/Boston: Walter de Gruyter GmbH, 2023, s. 137-162. De Gruyter STEM. ISBN 978-3-11-099972-3. Dostupné z: https://dx.doi.org/10.1515/9783110989380-011. |
Přiložené soubory | |
Popis | Cardiovascular diseases (CVDs) are the principal cause of death globally contributing to more than half of the mortality in Europe (42% on males and 51% on females) (Gillespie et al., 2013, Mozaffarian et al., 2015). There is growing interest in studying etiology, hallmarks, progress, and improved therapies for CVDs. Genetic background and cellular phenotypes are frequent morbidity and mortality causes (Aistrup et al., 2009, Stienen, 2015, van der Velden and Stienen, 2019), but those are not readily accessible for diagnostics. Stem-cell-derived cardiomyocytes (CMs) thus stands for readily available and ethically uncompromised model for basic research. |
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