Ictal connectivity changes induced by pulvinar stimulation correlate with improvement of awareness

• Autoři: DEUTSCHOVÁ Barbora; PIZZO F.; GIUSIANO B.; VILLALON S.M.; CARRON R.; BENAR C.; BARTOLOMEI F.
• Rok publikování: 2021
• Druh: Článek v odborném periodiku (nerecenzovaný)
• Fakulta / Pracoviště MU: Středoevropský technologický institut
• Popis: In patients with epilepsy, alteration of awareness (AOA) during seizures is a disabling feature that can potentially lead to serious consequences such as falls and injuries. Regarding the neural mechanisms underlying AOA in focal seizures, some hypotheses have been put forward. In temporal lobe epilepsy, AOA has been related to the extension of the discharge to subcortical structures and to subsequent widespread inhibition [1] or disturbed synchrony process [2] of the fronto-parietal association cortices.

Související projekty

• Subkortikální jádra a kortikální funkce z perspektivy hluboké mozkové stimulace