Fluorine Labeling as a Versatile Tool for Probing Nucleic Acid Folding and Interactions by NMR Spectroscopy

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This publication doesn't include Faculty of Economics and Administration. It includes Central European Institute of Technology. Official publication website can be found on muni.cz.
Authors

ZLÍNSKÁ Vladimíra MATOUSEK Vaclav TRANTÍREK Lukáš RIGO Riccardo

Year of publication 2022
Type Article in Periodical
Magazine / Source ALDRICHIMICA ACTA
MU Faculty or unit

Central European Institute of Technology

Citation
Web https://www.sigmaaldrich.com/CZ/en/collections/aldrichimica-acta
Keywords F-19 NMR spectroscopy; F-19 probes; DNA; RNA; F-19-labeling approaches; nucleic acid folding; nucleic acid/small molecule interactions; nucleic acid/protein interactions; in vitro; in vivo
Description This mini-review provides an overview of approaches to F-19-labeling of nucleic acids. A special attention is paid to applications of F-19-labeled nucleic acids to resolve their polymorphism and characterize their folding and interactions with ligands and proteins in vitro and in living cells by using NMR spectroscopy.
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