Project information
Determination of markers, screening and early diagnostics of cancer diseases using highly automated processing of multidimensional biomedical images
(Biomarker)
- Project Identification
- 2B06052
- Project Period
- 7/2006 - 6/2011
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Health and quality of life
- MU Faculty or unit
- Faculty of Informatics
- Keywords
- zpracování obrazu; optická mikroskopie; buněčné jádro; prostorové uspořádání; exprese genů; mikročipy; nádorová onemocnění; diagnostické markery
- Cooperating Organization
-
Brno University of Technology
- Responsible person doc. RNDr. Pavel Smrž, Ph.D.
- Responsible person Ing. Miloslav Richter, Ph.D.
The aim of the project is to develop new approaches to the processing of image data from fluorescence microscopy and microarrays that, in combination with the research in genomics and proteomics techniques, will help with the determination of markers, screening and early diagnostics of cancer diseases.
Results
Publications
Total number of publications: 121
2010
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Isolation of granulocytes: Which transcriptome do we analyze neutrophils or eosinophils?
FOLIA BIOLOGICA, year: 2010, volume: 56, edition: 6
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Quantification of Fluorescent Spots in Time Series of 3-D Confocal Microscopy Images Based on the HMAX Transform
Year: 2010, type: Conference abstract
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Quantification of Fluorescent Spots in Time Series of 3D Confocal Microscopy Images of Endoplasmic Reticulum Exit Sites Based on the HMAX Transform
Proceedings of SPIE Medical Imaging, year: 2010
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Simultaneous Tracking of Multiple Objects Using Fast Level Set-Like Algorithm
6th Doctoral Workshop on Mathematical and Engineering Methods in Computer Science, year: 2010
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SUV39h- and A-type Lamin-Dependent Telomere Nuclear Rearrangement
Journal of Cellular Biochemistry, year: 2010, volume: 109, edition: 5, DOI
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SUV39h-independent association of HP1b with fibrillarin-positive nucleolar regions
Chromosoma, year: 2010, volume: 119, edition: 3, DOI
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The role of chromatin condensation during granulopoiesis in the regulation of gene cluster expression
Epigenetics, year: 2010, volume: 5, edition: 8, DOI
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Time lapse living cells microscopy for studying CML: Preparation of Abl1- and Bcr/Abl - fluorescent protein vectors using Gateway technology
Advances in Molecular and Cancer Biology, 2010, year: 2010
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To divide or not to divide? How human embryonic stem cells deal with extra chromosomes?
Year: 2010, type: Appeared in Conference without Proceedings
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Too much of a good thing can harm: deregulation of centrosome number in human embryonic stem cells
Year: 2010, type: Conference abstract