Project information
Structural biophysics of macromolecules
- Project Identification
- GD204/03/H016
- Project Period
- 1/2003 - 12/2006
- Investor / Pogramme / Project type
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Czech Science Foundation
- Doctor grants
- MU Faculty or unit
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Faculty of Science
- prof. RNDr. Viktor Brabec, DrSc.
- prof. RNDr. Jaroslav Koča, DrSc.
- Keywords
- DNA, proteins, structure, cancer, antitumor drugs
The major objective of this project is to support, coordinate and make more effective scientific and research activities within the doctoral study program in the field of molecular biophysics and biology. Realization of this project will result incoordin ated activities within this doctoral study program of two research institutions in Brno with related and complementary scientific orientations in the fields of molecular biophysics and biology, namely the Faculty of Sciences of the MasarykUniversity - Na tional Center for Biomolecular Research and Institute of Biophysics, Academy of Sciences of the Czech Republic. A broader methodological orientation of the students participating in this project will be made possible by the use ofcomplementary and excell ent methodologies and instrumentation for research focused on the studies of structure of biomacromolecules and their interactions with the aid of the methods of molecular biophysics and biology.
Publications
Total number of publications: 40
2007
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Program for Analysis of Internal Motion in Molecular Dynamics Simulation
Konference mladých vědeckých pracovníků "Strukturní biofyzika makromolekul", year: 2007
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Purine derivatives: Substituent effects as monitored by NMR
Year: 2007, type: Conference abstract
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Structure of Bombyx mori chemosensory protein 1 in solution
Archives of Insect Biochemistry and Physiology, year: 2007, volume: 66, edition: 3
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Tryptophane as a Rotating Flap: Omega Loop Dynamics in Acetylcholinesterase
Year: 2007, type: Conference abstract
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UNRAVELING THE PROBLEMS OF PROTEIN - SACCHARIDE INTERACTIONS VIA COMPUTATIONAL CHEMISTRY
Materials structure, year: 2007, volume: 14, edition: 1
2006
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DIFFERENT MECHANISMS OF CDK5 AND CDK2 ACTIVATION AS REVEALED BY CDK5/P25 AND CDK2/CYCLIN A DYNAMICS
The Journal of biological chemistry, year: 2006, volume: 281, edition: 11
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Effect of Solvation on Pinched Cone-Pinched Cone Interconversion of Tetraethoxycalix[4]arene and Tetraethoxythiacalix[4]arene
Journal of Physical Chemistry A, year: 2006, volume: 110, edition: 3
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NMR Distance Restraints At Low Temperatures: Application To DNA Hairpin
International school on High field NMR spectroscopy for solids and liquids, year: 2006
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Optimized and parallelized implementation of the electronegativity equalization method and the atom-bond electronegativity equalization method
J Comput Chem, year: 2006, volume: 27, edition: 3
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RNA kink-turns as molecular elbows: Hydration, cation binding, and large-scale dynamics
Structure, year: 2006, volume: 14, edition: 5