Role of HMGB Proteins in Chromatin Dynamics and Telomere Maintenance in Arabidopsis thaliana

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Authors

PROCHÁZKOVÁ SCHRUMPFOVÁ Petra FOJTOVÁ Miloslava MOKROŠ Petr GRASSER Klaus D. FAJKUS Jiří

Year of publication 2011
Type Article in Periodical
Magazine / Source CURRENT PROTEIN & PEPTIDE SCIENCE
MU Faculty or unit

Central European Institute of Technology

Citation
Field Genetics and molecular biology
Keywords TRANSCRIPTION FACTOR DOF2; MOBILITY GROUP PROTEINS; DNA-BINDING; MAMMALIAN TELOMERES; METHYLATION; HETEROCHROMATIN; RNA; PLANTS; STRESS; REPAIR
Description HMGB proteins play important role in dynamic changes of chromatin structure. Here, we summarise the roles of plant HMGB proteins in regulation of chromatin structure and dynamics and report on the newly identified role of AtHMGB1 protein in the regulation of plant telomere length. Astonishingly, contrary to mice mHMGB1 homologue, AtHMGB1 does not affect telomerase activity and AtHMGB1 loss or overexpression does not cause any obvious changes in chromatin architecture.
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