Flow Cytometric Phenotyping and Analysis of T Regulatory Cells in Multiple Myeloma Patients

Investor logo

Warning

This publication doesn't include Faculty of Economics and Administration. It includes Faculty of Medicine. Official publication website can be found on muni.cz.
Authors

MUTHU RAJA Karthick Raja KOVÁŘOVÁ Lucie ŠTOSSOVÁ Jana HÁJEK Roman

Year of publication 2011
Type Article in Periodical
Magazine / Source Klinická onkologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords Tregs; flow cytometry; multiple myeloma; thalidomide
Description Multiple myeloma (MM) is a plasma cell (PC) disorder and associated with immune impairments. Flow cytometry based phenotyping and quantification of regulatory T cells (Tregs) enable to monitor the immune status of myeloma patients. Apart from enumeration of Tregs, functional characterization using proliferation or suppression assay adds key value in demonstrating the functional value of Tregs. Our study revealed that in MM patients Tregs are elevated compared to healthy subjects, which demonstrate the immune deregulation in MM.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.