Lectins from pathogens: mystery of life

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Authors

WIMMEROVÁ Michaela

Year of publication 2010
MU Faculty or unit

Faculty of Science

Citation
Description lectins from pathogens, which can mediate recognition and adhesion to host cells, can be important virulence factors. The combination of binding experiments (isothermal titration microcalorimetry, surface plasmon resonance,...) and X-ray crystallography approaches is used to decipher the thermodynamical and structural basis for high affinity binding of these lectins to host carbohydrates.
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