LC with off-line MALDI mass spectrometry for analysis of bioactive compounds

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Authors

HÉGROVÁ Blanka PEŠ Ondřej YEUNG Edward S. PREISLER Jan

Year of publication 2010
Type Article in Proceedings
Conference X. pracovní setkání fyzikálních chemiků a elektrochemiků - sborník příspěvků
MU Faculty or unit

Faculty of Science

Citation
Field Analytic chemistry
Keywords LC; off-line spojení; hmotnostní spektrometrie; nepolární látky
Description Biologically active compounds include an important class of a large number of polar and nonpolar compounds, which influence significantly organisms. MALDI mass spectrometry is a commonly used technique for analysis of polar biopolymers with detection limits going down to amol levels. Ionization of nonpolar compounds, such as sterols in positive mode was performed by silver ion cationization using silver nanoparticles as the MALDI matrix.
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