Aspergillus fumigatus lectins -  how to stay in touch

Houser,  Josef; Komárek,  Jan; Kostlánová,  Nikola; Ciocci, Gianluca; Imberty,  Anne; Wimmerová,  Michaela

Aspergillus fumigatus lectins - how to stay in touch

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Title in English	Aspergillus fumigatus lectins - how to stay in touch
Authors	HOUSER Josef KOMÁREK Jan KOSTLÁNOVÁ Nikola CIOCCI Gianluca IMBERTY Anne WIMMEROVÁ Michaela
Year of publication	2010
Type	Conference abstract
MU Faculty or unit	Faculty of Science
Citation
Description	Saprophytic fungus Aspergillus fumigatus is widespread alergen and an important pathogen for immunocompromised patients as well. Typical way, which many pathogens including Aspergillus utilize for binding to host-cells, is via sugar-binding proteins - lectins. In our research group we combine structural and functional approaches to precisely describe lectins' binding properties. Together with bioinformatics and molecular modeling we build up a complex picture of these biologicaly and medicaly important macromolecules.
Related projects:	Proteins in metabolism and interaction of organisms with the environment Biomolecular centre Design of Carbohydrates and Glycomimetics as Antibacterial and Antiviral Drugs Lectins from human pathogens - structure, function, engineering Molekulární a strukturní biologie vybraných cytostatik. Od mechanických studií k chemoterapii rakoviny