Nestin expression in human tumors and tumor cell lines
| Authors | |
|---|---|
| Year of publication | 2010 |
| Type | Article in Periodical |
| Magazine / Source | Neoplasma |
| MU Faculty or unit | |
| Citation | |
| Field | Oncology and hematology |
| Keywords | nestin; intermediate filaments; cytoskeleton; human tumors; angiogenesis; cancer stem cells |
| Description | The aim of this review is to summarize current knowledge on nestin expression in human tumors and corresponding tumor cell lines, as well as recent findings on the intracellular localization of nestin in human tumor cells, especially with regard to the possible correlation between nestin expression and the malignant phenotype of transformed cells. Nestin expression in vascular endothelial cells during angiogenesis is also reviewed. Special attention is paid to the detection of nestin in cancer stem cells. |
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