LOX/COX inhibitors may potentiate the antineoplastic effect of retinoids: in vitro study in neuroblastoma and medulloblastoma cell lines.

Lojová,  Martina; Chlapek,  Petr; Loja,  Tomáš; Zitterbart,  Karel; Hermanová,  Markéta; Štěrba,  Jaroslav; Veselská,  Renata

LOX/COX inhibitors may potentiate the antineoplastic effect of retinoids: in vitro study in neuroblastoma and medulloblastoma cell lines.

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Authors	RÉDOVÁ Martina CHLAPEK Petr LOJA Tomáš ZITTERBART Karel HERMANOVÁ Markéta ŠTĚRBA Jaroslav VESELSKÁ Renata
Year of publication	2009
Type	Article in Proceedings
Conference	Genes and Cancer - 26th Meeting
MU Faculty or unit	Faculty of Science
Citation
Field	Oncology and hematology
Keywords	neuroblastoma; medulloblastoma; caffeic acid; celecoxibe; all-trans retinoic acid; cell differentiation
Description	Study is focused on the detailed examination of the effect of combined application of the LOX/COX inhibitors with ATRA in established neuroblastoma and medulloblastoma cell lines.
Related projects:	Molecular basis of cell and tissue regulations Modulace antineoplastického efektu retinoidů LOX/COX inhibitory na modelu dětských solidních nádorů: in vitro studie Molecular mechanisms of the cell proliferation and differentiation