LOX/COX inhibitors: possible way to potentiate the antineoplastic effect of retinoids in neuroblastoma and medulloblastoma cell lines.

Lojová,  Martina; Chlapek,  Petr; Loja,  Tomáš; Zitterbart,  Karel; Hermanová,  Markéta; Štěrba,  Jaroslav; Veselská,  Renata

LOX/COX inhibitors: possible way to potentiate the antineoplastic effect of retinoids in neuroblastoma and medulloblastoma cell lines.

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Authors	RÉDOVÁ Martina CHLAPEK Petr LOJA Tomáš ZITTERBART Karel HERMANOVÁ Markéta ŠTĚRBA Jaroslav VESELSKÁ Renata
Year of publication	2009
Type	Article in Proceedings
Conference	International Journal of Mol. Medicine 24 (Sup. 1) - the 14th World Congress on Advances in Oncology and the 12th International Symposium on Molecular Medicine.
MU Faculty or unit	Faculty of Science
Citation
Field	Oncology and hematology
Keywords	neuroblastoma; medulloblastoma; caffeic acid; celecoxibe; all-trans retinoic acid; cell differentiation
Description	Study is focused on the detailed examination of the effect of combined application of the LOX/COX inhibitors with ATRA in established neuroblastoma and medulloblastoma cell lines.
Related projects:	Molecular basis of cell and tissue regulations Modulace antineoplastického efektu retinoidů LOX/COX inhibitory na modelu dětských solidních nádorů: in vitro studie Molecular mechanisms of the cell proliferation and differentiation