Genotype Association of C(-735)T Polymorphism in Matrix Metalloproteinase 2 Gene with G(8002)A Endothelin 1 Gene with Plaque Psoriasis

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Authors	VAŠKŮ Vladimír VAŠKŮ Anna TSCHÖPLOVÁ Svatava IZAKOVIČOVÁ HOLLÁ Lydie SEMRÁDOVÁ Věra VÁCHA Jiří
Year of publication	2002
Type	Article in Periodical
Magazine / Source	Dermatology
MU Faculty or unit	Faculty of Medicine
Citation
Field	Dermatovenerology
Keywords	MMP-2; Endothelin-1; Gene polymorphism; Plaque psoriasis
Description	Excessive angiogenesis is one of the characteristic features of psoriasis. To determine the possible genetic background of neo-angiogenesis in plaque psoriasis, frequent polymorphisms in matrix metalloproteinase 2(MMP-2) and endothelin 1(ET-1)genes were studied.
Related projects:	Molecular pathophysiology of selected multigenic related to civilization diseases