Detection and treatment of molecular relapse in acute myeloid leukemia with RUNXa, CBFB, MLL gene translocations, or NPMI mutation. Frequent quantitative monitoring of molecular markers in different compartments and correlation with WT1 gene expression.

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Authors

DOUBEK Michael PALÁSEK Ivo POSPÍŠIL Z. STRUNCOVÁ S. DVOŘÁKOVÁ Dana BORSKÝ M. KLABUSAY Martin BRYCHTOVÁ Y. KREJČÍ Marta MAYER Jiří

Year of publication 2008
Type Article in Periodical
Magazine / Source Annals of Hematology
MU Faculty or unit

Faculty of Medicine

Citation
Field Oncology and hematology
Keywords ACUTE LYMPHOBLASTIC-LEUKEMIA; FUSION TRANSCRIPTS; PROGNOSTIC VALUE
Description Frequent quantitative monitoring of fusion transcripts is useful for reliably predicting hematological relapse in AML patients. Treatment for molecular relapse of AML can be successful.
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