Úloha genetické predispozice při vzniku a rozvoji alergického astmatu

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Title in English	The role of genetic predisposition in susceptibility and development of allergic asthma
Authors	IZAKOVIČOVÁ HOLLÁ Lydie
Year of publication	2008
Type	Article in Periodical
Magazine / Source	Alergie
MU Faculty or unit	Faculty of Medicine
Citation
Field	Epidemiology, infectious diseases and clinical immunology
Keywords	gene; polymorphism; haplotype; predisposition; NOS; asthma; multifactorial
Description	Allergic diseases belong to a group of multifactorial disorders. Interactions of genetic and environmental factors play an important role in their pathogenesis. Although genetic research is very complicated, it is necessary for our understanding of etiopathogenesis and for possible development of new drugs for treatment of allergic iflammation.
Related projects:	Genetické determinanty pro-/antioxidační rovnováhy v patogeneze respiračních nemocí