THE ASSOCIATION OF INTERLEUKIN-4 (IL-4) HAPLOTYPES WITH CHRONIC PERIODONTITIS IN A CZECH POPULATION

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Authors	IZAKOVIČOVÁ HOLLÁ Lydie FASSMANN Antonín AUGUSTÍN Peter HALABALA Tomáš ZNOJIL Vladimír VANĚK Jiří
Year of publication	2008
Type	Article in Periodical
Magazine / Source	J Periodontol
MU Faculty or unit	Faculty of Medicine
Citation
Field	ORL, ophthalmology, stomatology
Keywords	periodontitis; gene; polymorphism; IL-4; interleukin; haplotype
Description	Cytokine gene polymorphisms are known to influence susceptibility and disease course of many chronic disorders. Recently, interleukin-4 (IL-4) gene polymorphisms have been associated with aggressive periodontitis. The aim of this study was to test differences in distribution of the IL-4 alleles, genotypes and haplotypes between patients with chronic periodontitis (CP) and healthy controls in a Czech population.
Related projects:	Analýza polymorfizmů v genech prozánětlivých a remodelačních faktorů ve vztahu k imunitní reakci a klinickému stavu pacientů s parodontitidou