Comparison of Dendritic Cells in Healthy Volunteers and Subjects with Monoclonal Gammopathy and/or Multiple Myeloma
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Dendritic cells are highly specialised antigen-presenting cells, which can be used for immunotherapy trials. Functionally normal DCs play a critical role in the activation and potentiation of tumour antigen-specific responses, but in some cases they can be defective. The aim of study were analysis of phenotype, finding of differences and/or functional defects in DCs generated from multiple myeloma and monoclonal gammopathy of unknown significance subjects when compared with healthy volunteers under serum-free and/or autologous conditions. |
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