Effect of ferB mutation on the sensitivity of Paracoccus denitrificans to quinones
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Proceedings |
| Conference | FEBS Journal Supplement 32nd FEBS Congress Abstracts |
| MU Faculty or unit | |
| Citation | |
| Field | Biochemistry |
| Keywords | quinone; reductase; stoichiometry; redox cycling |
| Description | By using insertional mutagenesis, we have demonstrated that a putative quinone reductase encoded by the ferB gene confers increased susceptibility to 1,4-naphthoquinones, but not to 1,4-benzoquinones. This difference may be due to a one-electron reduction of naphthoquinones to reactive radical semiquinones and subsequent generation of oxygen reactive species. |
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