MCP-1 and CCR-2 gene polymorphisms in Czech patients with allergic disorders

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Authors

MRÁZEK František IZAKOVIČOVÁ HOLLÁ Lydie JURAJDA Michal PETŘEK Martin

Year of publication 2007
Type Article in Periodical
Magazine / Source Eur.Respir.J.
MU Faculty or unit

Faculty of Medicine

Citation
Field Immunology
Keywords MCP-1; CCR-2; gene; polymorphism; allergy
Description The aim of this study was to test the genetic association between the MCP-1 -2518A/G and the CCR2 V64I polymorphisms and asthma/allergy in the Czech population. Our study supports the idea that MCP-1 but not CCR2 gene variant may participate in the pathogenesis of particular allergic phenotypes at least in the Czech population.
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