Blood pressure regulation and physical activity in adolescents treated for malignant disease

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Authors

NOVÁKOVÁ Zuzana ZÁVODNÁ Eva DOSTALOVÁ KOPEČNÁ Lenka HRSTKOVÁ Hana HONZÍKOVÁ Nataša FIŠER Bohumil JÍRA Miroslav

Year of publication 2005
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description The subjects treated for a malignant tumour by the anthracycline antitumour agents in comparison to healthy controls and subjects trated for a tumour without anthracyclines had increased parasympathetic and decreased sympathetic tonic activity that could be documented on lower values of systolic blood pressure and higher baroreflex sensitivity. This increase of parasympathetic reflex control of the heart after antitumour therapy is not be a sign of a physical training as it is seen in healthy population, but we can explain it by cardiotoxic or neurotoxic effect of anthracycline therapy. Vice versa, we could explaine decreased body parameters and physical activity by the anthracycline side effects.
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