Ecstasy induces both initiation and expression of behavioural sensitization to its stimulatory effects in mice.

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Authors	LANDA Leoš ŠLAIS Karel ŠULCOVÁ Alexandra
Year of publication	2005
Type	Article in Periodical
Magazine / Source	European Neuropsychopharmacology
MU Faculty or unit	Faculty of Medicine
Citation
Field	Pharmacology and pharmaceutical chemistry
Keywords	behavioural sensitization; ecstasy; open field; mice
Description	The results showed: a) significant stimulatory influence of MDMA after the acute administration, b) development of significant sensitization after MDMA repeated treatment, c) expression of sensitization after MDMA challenge dose given after 6 days of washout from the repeated MDMA treatment.
Related projects:	The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.