Gender differences in sensitization to methamphetamine effects on locomotion in rats
| Authors | |
|---|---|
| Year of publication | 2005 |
| Type | Article in Periodical |
| Magazine / Source | Homeostasis in Health and Diseases |
| MU Faculty or unit | |
| Citation | |
| Field | Pharmacology and pharmaceutical chemistry |
| Keywords | gender differences; behavioural sensitization; methamphetamine; rats |
| Description | On the contrary to results of previous study realized in mice, in rats on the same dosage regimen a phenomenon of behavioural sensitization to methamphetamine stimulatory effects on locomotion was not confirmed. Instead, with the exception on the Day 21 in females, a significant dose dependent decrease (tolerance) of distance run appeared following the repeated drug treatment and female rats displayed a greater tolerance than males did. |
| Related projects: |