Degradation of b-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26.

Nagata, Yuji; Prokop,  Zbyněk; Sato, Yukari; Jeřábek,  Petr; Kumar, Ashawi; Ohtsubo, Yoshiyuhi; Tsuda, Masataka; Damborský,  Jiří

Degradation of b-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26.

Warning

This publication doesn't include Faculty of Economics and Administration. It includes Faculty of Informatics. Official publication website can be found on muni.cz.

Authors	NAGATA Yuji PROKOP Zbyněk SATO Yukari JEŘÁBEK Petr KUMAR Ashawi OHTSUBO Yoshiyuhi TSUDA Masataka DAMBORSKÝ Jiří
Year of publication	2005
Type	Article in Periodical
Magazine / Source	Applied and Environmental Microbiology
MU Faculty or unit	Faculty of Informatics
Citation
Web	http://loschmidt.chemi.muni.cz/peg/abstracts/aem05a.html
Field	Genetics and molecular biology
Keywords	b-hexachlorocyclohexane; degradation; haloalkane dehalogenase LinB; HCH; UT26
Description	-Hexachlorocyclohexane (b-HCH) is the most recalcitrant among the a-, b-, g-, and d-isomers of HCH, and causes serious environmental pollution problems. We demonstrate here that the haloalkane dehalogenase LinB, reported earlier to mediate the second step in the degradation of g-HCH in Sphingomonas paucimobilis UT26, metabolizes b-HCH to produce 2,3,4,5,6-pentachlorocyclohexanol.
Related projects:	Biomolecular Center