Microwave-assisted solvent-free synthesis of hexahydrochromeno[4,3-b]pyrroles

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Authors

POSPÍŠIL Jiří POTÁČEK Milan

Year of publication 2004
Type Article in Periodical
Magazine / Source European Journal of Organic Chemistry
MU Faculty or unit

Faculty of Science

Citation
Field Organic chemistry
Keywords cycloaddition; microwave-assisted synthesis; solvent-free synthesis; ylides
Description Microwave-assisted solvent-free synthesis of hexahydrochromeno[4,3-b]pyrroles is reported. Intramolecular 1,3-dipolar cycloaddition under these conditions proceeds in 15 min with 80% yields. Moreover, pronounced steric requirements of alkyl substituents towards 1,3-dipolar cycloaddition are observed.
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