Vliv předozáření na některé biochemické parametry maligních nádorů mléčné žlázy: receptory steroidních hormonů

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Title in English Influence of pre-irradiation on some biochemical parameters of breast malignant tumors: steroid hormone receptors
Authors

LANG B.A. ČERNOCH M. ŠIMÍČKOVÁ M. NEKULOVÁ M. FORBELSKÁ Marie PECEN L. EBEN K. VONDRÁČEK J. PAČOVSKÝ Z. VERMOUSEK I.

Year of publication 2001
Type Article in Periodical
Magazine / Source Klinická onkologie
MU Faculty or unit

Faculty of Science

Citation
Field Oncology and hematology
Keywords breast cancer; estrogen-receptor; progesterone-receptor; radiotherapy; cancer cell; ionizing radiation
Description Our results confirm the differences in the expression of steroid hormones in malignant breast tumours with and without pre-irradiation. The results seem to support the assumption that preoperative irradiation of breast tumours may impair the function of estrogen a progesterone signalling pathways in the tumour tissue. The authors believe that a thorough understanding of the consequences irradiation may produce in both healthy and oncologically affected tissue of the mammary gland remains a clinically topical issue even today.
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