Vliv předozáření na některé biochemické parametry maligních nádorů mléčné žlázy: receptory steroidních hormonů

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Title in English	Influence of pre-irradiation on some biochemical parameters of breast malignant tumors: steroid hormone receptors
Authors	LANG B.A. ČERNOCH M. ŠIMÍČKOVÁ M. NEKULOVÁ M. FORBELSKÁ Marie PECEN L. EBEN K. VONDRÁČEK J. PAČOVSKÝ Z. VERMOUSEK I.
Year of publication	2001
Type	Article in Periodical
Magazine / Source	Klinická onkologie
MU Faculty or unit	Faculty of Science
Citation
Field	Oncology and hematology
Keywords	breast cancer; estrogen-receptor; progesterone-receptor; radiotherapy; cancer cell; ionizing radiation
Description	Our results confirm the differences in the expression of steroid hormones in malignant breast tumours with and without pre-irradiation. The results seem to support the assumption that preoperative irradiation of breast tumours may impair the function of estrogen a progesterone signalling pathways in the tumour tissue. The authors believe that a thorough understanding of the consequences irradiation may produce in both healthy and oncologically affected tissue of the mammary gland remains a clinically topical issue even today.
Related projects:	Functional-differential equations and mathematical-statistical models