VLIV GLUTAMÁTU A SPECIFICKÉHO ANTAGOMIRU NA SPONTÁNNÍ ELEKTRICKOU AKTIVITU HIPPOKAMPÁLNÍCH NEURONŮ

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Title in English Effect of glutamate and specific antagomir on spontaneous electrical activity of hippocampal neurons
Authors

POLEDŇÁKOVÁ Anna GOLIÁŠOVÁ Zita ŠVECOVÁ Olga KRÁL Martin BRÁZDIL Milan BÉBAROVÁ Markéta

Year of publication 2024
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation POLEDŇÁKOVÁ, Anna, Zita GOLIÁŠOVÁ, Olga ŠVECOVÁ, Martin KRÁL, Milan BRÁZDIL and Markéta BÉBAROVÁ. VLIV GLUTAMÁTU A SPECIFICKÉHO ANTAGOMIRU NA SPONTÁNNÍ ELEKTRICKOU AKTIVITU HIPPOKAMPÁLNÍCH NEURONŮ (Effect of glutamate and specific antagomir on spontaneous electrical activity of hippocampal neurons). In 67. Studentská vědecká konference LF MU. 2024.
Description The pilot data suggested an inhibitory effect of antagomir againts miR-142-5p on spontaneous electrical activity of neurons. If the final data confirmed this finding, a decrease in the expression of this miRNA might be considered as a potential alternative treatment of phyrmacoresistant epilepsy.
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