Exploring Real-World Data Based Financing Models For Lung Cancer Immunotherapy In The Czech Republic
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| Year of publication | 2024 |
| Type | Conference abstract |
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| Description | Immunotherapy is increasingly used in the treatment of metastatic lung cancer, with coverage provided by Czech public health insurance for specific indications. This study assesses the potential budgetary impact of implementing performance-based risk-sharing agreements (PBRSA) for immunotherapy. A retrospective analysis of 127 lung cancer patients treated with immunotherapy (including 42 receiving nivolumab) at the Masaryk Memorial Cancer Institute revealed discrepancies between real-world progression-free survival (PFS) and clinical trial data. Treatment costs varied significantly based on treatment success, with unsuccessful cases averaging EUR9,300 per patient and successful cases exceeding EUR29,700. A PBRSA model could shift up to 66% of costs for unsuccessful treatments to manufacturers, potentially funding additional patients. This study highlights the importance of PBRSA in addressing the economic challenges of high-cost therapies, improving affordability, and ensuring sustainable access for patients. |
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