Inhibitory kinázy Haspin

Warning

This publication doesn't include Faculty of Economics and Administration. It includes Faculty of Science. Official publication website can be found on muni.cz.
Title in English Haspin kinase inhibitors
Authors

PARUCH Kamil

Year of publication 2022
MU Faculty or unit

Faculty of Science

Description Protein kinases are particularly interesting therapeutic targets for modern cancer therapy; to date, more than 35 low molecular weight inhibitors have been approved for clinical use. While some kinases have long been established as attractive targets for pharmacological inhibition, others have come to the fore relatively recently. Haspin kinase inhibitors exhibit attractive broad-spectrum antitumor activity in cell lines. In addition, the existing lead compound MU1464 also has a good pharmacokinetic profile, making it highly likely that these compounds may be therapeutically useful in vivo.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.