Hodnocení endotelové vrstvy rohovky u nositelů kontaktních čoček pomocí endoteliálního mikroskopu
| Title in English | Assessment of corneal endothelial layer in contact lens wearers with the aid of an endothelial microscope |
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| Authors | |
| Year of publication | 2022 |
| Type | Article in Periodical |
| Magazine / Source | Česká a Slovenská oftalmologie |
| MU Faculty or unit | |
| Citation | |
| Web | https://www.prolekare.cz/casopisy/ceska-slovenska-oftalmologie/2022-6-7/hodnoceni-endotelove-vrstvy-rohovky-u-nositelu-kontaktnich-cocek-pomoci-endotelialniho-mikroskopu-133054 |
| Doi | http://dx.doi.org/10.31348/2022/30 |
| Keywords | endothelial cell;endothelial microscope;soft contact lens;hard contact lens;hybrid contact lens |
| Description | Aims: The main aim of our study was to demonstrate the difference in endothelial cell density between a group of keratoconus contact lens users and non-contact lens users (without keratoconus). Material and methods: In our study we had data from 96 subjects with an average age of 40.5 ±14.05 years. For the purposes of our study, we worked with each eye separately for each subject (n = 192). Keratoconus (research group) was diagnosed in 97 eyes. The mean age of the patients in the research group was 41.9 ±10.6 years. Keratoconus was not diagnosed in the remaining 95 eyes (control group). The mean age of the patients in the control group was 39.5 ±16.6 years. In the keratoconus group, the patients wore hard contact lenses (HCL) in a total of 43 eyes, hybrid contact lenses (HbCL) in 48 eyes and soft contact lenses (SCL) in 6 eyes. The average total period of contact lens use in the research group was 10.6 ±2.36 years. Results: The average number of endothelial cells in the research group was 2607.11 ±298.45 cells per mm2. The average number of endothelial cells in the control group was 2831.94 ±523.51 cells per mm2. We tested these two variables using a T-test, which showed a statistically significant difference (p < 0.001). A statistically significant difference in the mean endothelial cell count related to patient age and use / non-use of contact lenses of two types was demonstrated only in the under-40 group in a comparison of the non-contact and keratoconus group with the keratoconus group using HCL (p = 0.02). A statistically significant difference in the length of contact lens wear was demonstrated between the keratoconus-free group with or without SCL and the keratoconus group when wearing HCL or HbCL for more than 20 years (p = 0.01 and p = 0.02). For HbCL users, this difference was demonstrated also after 15 years of wearing (p = 0.001). Conclusion: From our results we can conclude that there is a difference in endothelial cell density between patients with and without keratoconus. |
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