Benefits of F-18-FET PET in preoperative assessment of glioma heterogeneity demonstrated in two case reports

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Title in English Benefity vyšetření 18F-FET PET v předoperačním posouzení heterogenity gliálních tumorů demonstrovány na dvou kazuistikách
Authors

VALEKOVÁ Hana VAŠINA Jiří ŘEHÁK Zdeněk HODOLIC M. HENDRYCH Michal KAZDA Tomáš POSPÍŠIL Petr SOLÁR Peter MACKERLE Zdeněk JANČÁLEK Radim

Year of publication 2021
Type Article in Periodical
Magazine / Source Ceska a slovenska neurologie a neurochirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.csnn.eu/en/journals/czech-and-slovak-neurology-and-neurosurgery/2021-4-9/benefits-of-18f-fet-pet-in-preoperative-assessment-of-glioma-heterogeneity-demonstrated-in-two-case-reports-128182
Doi http://dx.doi.org/10.48095/cccsnn2021405
Keywords F-18-FET PET; glioma heterogeneity; preoperative assessment
Description Gliomas are intra-axial brain tumors with high biological heterogeneity. MRI is still considered the gold standard of diagnostic algorithms. Especially in gliomas with atypical enhancement patterns, where foci with different grading can coexist, PET could increase sensitivity and specificity of pre-surgery imaging by monitoring processes such as cell proliferation, membrane biosynthesis, and glucose consumption.
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